Caffeic acid phenethyl ester (CAPE) is an important active component of honeybee propolis extract and has been used in traditional medicine for a number of years. CAPE is a polyphenol that contains hydroxyl groups within a catechol ring, the molecular formula of CAPE is C! 17 H 16 O 4 ( 1, 2 ) ( Fig. 1 ).
Aim: Caffeic acid phenethyl ester (CAPE) has cytotoxic, apoptotic, and antiproliferative effects on various tumor cells, and is the most active component of propolis.
Caffeic acid phenethyl ester (CAPE) is a natural phenolic chemical compound. It is the ester of caffeic acid and phenethyl alcohol.. Natural occurrences. CAPE is found in a variety of plants. It is also a component of propolis from honeybee hives.. Potential pharmacology. A variety of in vitro pharmacology and effects in animal models have been reported for CAPE, but their clinical .
Database on Polyphenols in Foods. Showing all foods in which the polyphenol Caffeic acid is found Food Composition
Caffeic Acid Phenethyl Ester (CAPE) has beneficial effects on metabolic syndrome and vascular function which is important in the prevention of cardiovascular disease. However, there are no known studies about the effect of CAPE on fructose-induced vascular dysfunction.
May 29, 2014· Caffeic acid phenethyl ester (CAPE) is a bioactive compound of propolis extract. The literature search elaborates that CAPE possesses antimicrobial, antioxidant, anti-inflammatory, and cytotoxic properties. The principal objective of this review article is to sum up and critically assess the .
Biochem/physiol Actions A natural dietary phenolic compound found in plants that is an anti-oxidant. Inhibits the synthesis of leukotrienes that are involved in immunoregulation, inflammation and allergy.
Aug 10, 2017· Caffeic acid (3,4-dihydroxy-cinnamic acid) is an organic compound and a potent antioxidant. It can be found naturally in a wide range of plants. Caffeic acid is a …
Aug 20, 1996· Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B. K Natarajan, S Singh, T R Burke, Jr, D Grunberger, and B B Aggarwal Department of Molecular Oncology, University of Texas M.D. …
May 12, 2015· 3. Caffeic Acid Phenethyl Ester (CAPE) and Anticancer Effects. Caffeic acid phenethyl ester (CAPE) (Figure 1) is one of the main bioactive components extracted from honeybee hive propolis.CAPE is a strong antioxidant [26,27] and a lipophilic derivative of caffeic acid and a phenolic antioxidant structurally related to 3,4-dihydroxycinnamic acid.CAPE is a well-known NF-κB …